例骨髓坏死患者的实验室检查结果分析（完整版）(文档可以直接使用，也可根据实际需要修改使用,可编辑欢迎下载）海南医学2021年6月第24卷第12期HainanMedJ,Jun.2021,Vol.24,No.12?论著?9例骨髓坏死患者的实验室检查结果分析12陈新瑶,虞咏知12潮州?人民医院潮州医院)检验科、血液科,广东潮州521000【摘要】目的了解骨髓坏死BMN患者的实验室检查结果与原发病的关系。方法分析1997-2021年本院收治的9例骨髓坏死患者实验室检查结果,对其临床表现及原发病进行比较。结果实验室检查显示9例患者血清乳酸脱氢酶活性都明显增高,7例碱性磷酸酶活性升高;9例患者血红蛋白都明显减低其中6例50g/L;骨髓涂片中细胞形态模糊不清、大片融合、破碎、溶解;以骨痛、发热和进行性贫血为主要表现,且原发病多数为恶性疾病。结论骨髓坏死与恶性肿瘤密切相关,是一种少见的临床综合征,但实验室检查尤其是骨髓涂片细胞形态学检查仍是目前诊断骨髓坏死的主要手段,对于疑似患者应及时行骨髓穿刺检查。【关键词】骨髓坏死;乳酸脱氢酶;碱性磷酸酶;血常规【中图分类号】R446【文献标识码】A【文章编号】1003?6350(2021)12?1784?0212Laboratorytestsandresultanalysisof9casesofbonemarrownecrosis.CHENXin-yao,YUYong-zhi12DepartmentofClinicalLaboratory,DepartmentofHematology,ChaozhouMunicipalPeople'sHospital,Chaozhou521000,Guangdong,CHINA【Abstract】ObjectiveTounderstandtherelationshipoflaboratorytestsandprimarydiseaseinpatientswithbonemarrownecrosisBMN.MethodsThelaboratorytestresultsof9patientswithbonemarrownecrosistreatedinourhospi-talfrom1997to//.ultsLaborato-rytestsshowedthatthe9patients'serumlactatedehydrogenaseactivitywereallsignificantlyhigherthannormal,7ofthepa-tients'alkalinephosphataseweremoreactivethannormal,andthe9patients'hemoglobinwereallsignificantlyreduced50g/Lin6cases.Thebonemarrowsmearsshowedthatthecellswereblurred,brokenordissolving,orwithblockbusterfusion.Themainclinicalmanifestationswerebonepain,feverandanemia,andtheprimarydiseaseswerethemostmalignantdisease.ConclusionBonemarrownecrosisismostlyrelatedtomalignanciesandisrecognizedasararelyclinicalsyndrome.How-ever,laboratorytests,especiallymorphologicalexaminationofbonemarrowsmears,isstilltheprimarymeansofdiagnosisofbonemarrownecrosis.SuspectedpatientsofBMNshouldbecheckedbonemarrowpromptly.【Keywords】Bonemarrownecrosis;Lacticdehydrogenase;Alkalinephosphatase;Bloodroutinetest[2]骨髓坏死BMN是指骨髓中造血细胞和骨髓基质为3级:I级轻度坏死:骨髓坏死总范围低于整张骨面积不等的坏死,主要由赘生性疾患白血病、恶性肿瘤髓涂片的20%;Ⅱ级中度坏死:骨髓坏死总范围占[1]引起,也可见于败血症和弥散性血管内凝血DIC。整张骨髓涂片的20%~50%;Ⅲ级重度坏死:骨髓坏BMN预后较差,研究其各项实验室检查及病因,旨在进死总范围高于整张骨髓涂片的50%。一步为临床诊断提供可行性依据。本文对我院收