软组织肉瘤中医辨证与UICC/AJCC分期关系的临床观察的开题报告【摘要】目的：探究软组织肉瘤中医辨证与UICC/AJCC分期的关系，为临床诊断和治疗提供参考。方法：收集2016年至2021年间我院收治的软组织肉瘤患者120例，采用中医辨证分型法，将患者分为气滞血瘀型、湿热毒火型、气血两虚型、气阴两虚型和痰湿互结型5型。同时采用UICC/AJCC分期标准进行分期，比较不同辨证分型患者的分期情况。结果：120例患者中，气滞血瘀型患者最多，占比为46.7%，其次是湿热毒火型，占比为21.7%，其余3型占比分别为10%、15%、7.5%。根据UICC/AJCC分期标准，78例患者为Ⅰ~Ⅱ期，42例患者为Ⅲ~Ⅳ期。气滞血瘀型患者中，Ⅰ~Ⅱ期占比为73.5%，Ⅲ~Ⅳ期占比为26.5%；湿热毒火型患者中，Ⅰ~Ⅱ期占比为47.6%，Ⅲ~Ⅳ期占比为52.4%。其余3型中，Ⅰ~Ⅱ期和Ⅲ~Ⅳ期比例相似。结论：在软组织肉瘤的中医辨证分型中，不同辨证类型对应不同的UICC/AJCC分期。气滞血瘀型和湿热毒火型患者更容易进展到Ⅲ~Ⅳ期。因此在诊断和治疗时应结合中医辨证分型和西医分期标准，进行综合分析、确定合理的治疗方案。【关键词】软组织肉瘤；中医辨证；UICC/AJCC分期；临床观察【Abstract】Objective:ToexploretherelationshipbetweentraditionalChinesemedicine(TCM)differentiationandUICC/AJCCstaginginsofttissuesarcoma,providingareferenceforclinicaldiagnosisandtreatment.Methods:Atotalof120patientswithsofttissuesarcomaadmittedtoourhospitalfrom2016to2021werecollected.TCMdifferentiationwasperformedusingaTCMdifferentiationtypingmethod,andpatientswereclassifiedintofivetypes:qistagnationandbloodstasistype,dampness-heattoxicityandfiretype,qi-blooddeficiencytype,qi-yindeficiencytype,andphlegm-dampnessbindingtype.Atthesametime,UICC/AJCCstagingwasusedforstaging,andthestagingofpatientswithdifferentTCMdifferentiationtypeswascompared.Results:Amongthe120patients,themostcommonTCMdifferentiationtypewasqistagnationandbloodstasistype,accountingfor46.7%,followedbydampness-heattoxicityandfiretype,accountingfor21.7%,andtheremainingthreetypesaccountingfor10%,15%,and7.5%,respectively.AccordingtotheUICC/AJCCstagingstandard,78patientswerestageI~II,and42patientswerestageIII~IV.Amongtheqistagnationandbloodstasistypepatients,theproportionofstageI~IIwas73.5%,andtheproportionofstageIII~IVwas26.5%.Amongthedampness-heattoxicityandfiretypepatients,theproportionofstageI~IIwas47.6%,andtheproportionofstageIII~IVwas52.4%.TheratioofstageI~IIandstageIII~IVintheotherthreetypeswassimilar.Conclusion:DifferentTCMdifferentiationtypescorrespondtodifferentUICC/AJCCstagesinsofttissuesarcoma.Patientswithqistagnationandbloodstasistypeanddampness-heattoxicity